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Tittel Versjon Status
Revisjonsdato Publiseringsdato
Utgiver(e) Publikasjonstype
  • Norsk tittel - Nasjonalt handlingsprogram med retningslinjer for palliasjon i kreftomsorgen
  • Engelsk tittel -
  • Versjon - 5
  • Status - Publisert
  • IS-nr - 2285
  • ISBN - 978-82-8081-368-8
  • DOI -
  • Revisjonsdato - 26.03.2015
  • Neste revisjon -
  • Publikasjonsdato - 22.04.2010
  • Utløpsdato -
  • Utgiver(e) - Helsedirektoratet
  • Redaktør -
  • Publikasjonstype - Nasjonale retningslinjer
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  2. De Graeff A, Krol RJA. Constipation. Nation-wide guideline, Version: 2.0. Integraal Kankercentrum Nederland, 2010.
  3. Ahmedzai SH and Boland J. Constipation in people prescribed opioids. Clinical Evidence 2010;04:2407
  4. Miles C, Fellowes D, Goodman ML, Wilkinson SSM. Laxatives for the management of constipation in palliative care patients. Cochrane Database of Systematic Reviews 2006, Issue 4. Art.No.: CD003448. DOI: 10.1002/14651858.CD003448.pub2
  5. Mancini I and Bruera E. Constipation in advanced cancer patients. Support Care Cancer 1998;6:356-364
  6. McMillan S. Assessing and managing opiate-induced constipation in adults with cancer. Cancer control 2004;11(3)
  7. Woolery M, Bisanz A, Lyons HF, Gaido L, Yenulevich M, Fulton S, McMillan S. Evidence-based interventions for the prevention and management of constipation in patients with cancer. Clinical Journal of Oncology Nursing 2008;12:317-337
  8. Locke GR, Pemberton JH, Phillips SF. American gastroenterological association medical position statement: Guidelines on constipation. Gastroenterology 2000;119:1761-1778
  9. Smith S. Evidence-based management of constipation in the oncology patient. European Journal of Oncology Nursing 2001;5:18-25
  10. Clark K and Currow DC. Assessing constipation in palliative care within a gastroenterology framework. Palliat Med 2012;26:834-841
  11. Follwell M, Burman D, Le LW, Wakimoto K, Seccareccia D, Bryson J, Rodin G, Zimmermann C. Phase II study of an outpatient palliative care intervention in patients with metastatic cancer. J Clin Oncol 2008;27:206-213
  12. Librach SL, Bouvette M, de Angelis C, Farley J, Oneschuk D, Pereira JL, Syme A. Consensus recommendations for the management of constipation in patients with advanced, progressive illness. J Pain Symptom Manage 2010;40:761-773
  13. Ireland’s Health Services. Management of constipation in palliative care, clinical guideline v5 13.7.13:
  14. Clark K, Lam LT, Agar M, Chye R, Currow D. The impact of opioids, anticholinergic medications and disease progression on the prescription of laxatives in hospitalixed palliative care patients: a retrospective analysis. Palliat Med 2010;24:410-418
  15. Norsk legemiddelhåndbok, kapittel L12.10 Laksantia
  16. Tamayo AC, Diaz-Zuluaga PA. Management of opioid-induced bowel dysfunction in cancer patients. Support Care Cancer 2004;12:613-618
  17. Freedman MD, Schwartz HJ, Roby R, Fleisher S. Tolerance and efficacy of polyethylene glycol 3350/electrolyte solution versus lactulose in relieving opiate induced constipation: a double-blinded placebo-controlled trial. J Clin Pharmacol 1997;37:904-907
  18. Wirz S, Nadstawek J, Elsen C, Junker U, Wartenberg HC. Laxative management in ambulatory cancer patients on opioid therapy: a prospective, open-label investigation of polyethylene glycol, sodium picosulphate and lactulose. European Journal of Cancer Care 2012;21:131-140
  19. Agra Y, Sacristian A, Gonzalez M, Ferrari M, Portugues A, Calvo MJ. Efficacy of senna versus lactulose in terminal cancer patients treated with opioids. J Pain Symptom Manage 1998;15:1-7
  20. Droney J, Ross J, Gretton S, Welsh K, Sato H, Riley J. Constipation in cancer patients on morphine. Support Care Cancer 2008;16:453-459
  21. Caraceni A, Hanks G, Kaasa S, et al. Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. Lancet Oncology 2012;13:e58-68
  22. Clark AJ, Ahmedzai SH, Allan LG, Camacho F, Horbay GLA, Richarz U, Simpson K. Efficacy and safety of transdermal fentanyl and sustained-release oral morphine in patients with cancer and chronic non-cancer pain. Current Medical Research and Opinion 2004;20:1419-1428
  23. Radbruch L, Sabatowski R, Loick G, Kulbe C, Kasper M, Grond S, Lehmann KA. Constipation and the use of laxatives: a comparison between transdermal fentanyl and oral morphine. Palliat Med 2000;14:111-119
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  26. Meissner W, Leyendecker P, Mueller-Lissner S, Nadstawek J, Hopp M, Ruckes C, Wirz S, Fleischer W, Reimer K. A randomised controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced constipation. European Journal of Pain 2009;13:56-64.
  27. Löwenstein O, Leyendecker P, Hopp M, Schutter U, Rogers PD, Uhl R, Bond S, Kremers W, Nichols T, Krain B, Reimer K. Combined prolonged-release oxycodone and naloxone improves bowel function in patients receiving opioids for moderate-to-severe non-malignant chronic pain: a randomised controlled trial. Expert Opin Pharmacother 2009;10:531-543.
  28. Mancini IL, Hanson H, Neumann CM, Bruera E. Opioid type and other clinical predictors of laxative dose in advanced cancer patients: a retrospective study. Journal of Palliative Medicine 2000;3:49-56
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